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The role of transforming growth factor‐β1 and oxidative stress in podoconiosis pathogenesis

Identifieur interne : 005B58 ( Main/Exploration ); précédent : 005B57; suivant : 005B59

The role of transforming growth factor‐β1 and oxidative stress in podoconiosis pathogenesis

Auteurs : S. Addisu ; T. H. El-Metwally ; G. Davey [Éthiopie] ; Y. Worku ; M. A. Titheradge [Royaume-Uni]

Source :

RBID : ISTEX:F00DD67759AEED505008B60A91AF6FE0112E36AE

Descripteurs français

English descriptors

Abstract

Background  Podoconiosis (endemic nonfilarial elephantiasis) occurs in susceptible individuals who go barefoot in regions of irritant volcanic soil. Silicate particles absorbed via the skin are thought to induce an inflammatory process and a consequent endolymphangitis of the lower leg lymphatics.

Url:
DOI: 10.1111/j.1365-2133.2010.09652.x


Affiliations:


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<div type="abstract">Background  Podoconiosis (endemic nonfilarial elephantiasis) occurs in susceptible individuals who go barefoot in regions of irritant volcanic soil. Silicate particles absorbed via the skin are thought to induce an inflammatory process and a consequent endolymphangitis of the lower leg lymphatics.</div>
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